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1H-TETRAZOLE-1-ACETYL CHLORIDE

1H-TETRAZOLE-1-ACETYL CHLORIDE

CAS: 41223-92-1

Molecular Formula: C3H3ClN4O

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1H-TETRAZOLE-1-ACETYL CHLORIDE - Names and Identifiers

Name 1H-TETRAZOLE-1-ACETYL CHLORIDE
Synonyms Ceftezole Impurity 4
Ceftezole Impurity 10
Tetrazoleacetyl cholride
1H-TETRAZOLE-1-ACETYL CHLORIDE
2-(Tetrazol-1-yl)acetyl chloride
2-(1H-Tetrazol-1-yl)acetyl Chloride
2-(tetrazol-1-yl)acetic acid chloride
2-(1H-1,2,3,4-tetrazol-1-yl)acetyl chloride
CAS 41223-92-1

1H-TETRAZOLE-1-ACETYL CHLORIDE - Physico-chemical Properties

Molecular FormulaC3H3ClN4O
Molar Mass146.54
Density1.75±0.1 g/cm3(Predicted)
Boling Point263.3±42.0 °C(Predicted)
pKa0.36±0.10(Predicted)
UseUses Cephalosporin V, ceftezole, cefazolin intermediates.

1H-TETRAZOLE-1-ACETYL CHLORIDE - Production method

Glycine, potassium azide, and triethyl orthoformate are condensed and cyclized to generate 1H-tetrazolazole acetic acid, and then reacted with pentaphosphide at 30-80 ℃. The product is prepared by acylation and dehydrochlorination.

Last Update:2024-04-10 22:29:15
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